This site is intended only for healthcare professionals resident in the Republic of Ireland
A single-arm, open-label, non-randomised study to evaluate the safety and efficacy of BOSULIF in patients with chronic or advanced phase Ph+ CML who have failed prior treatment with TKIs.1,2
Many patients entered the study with a major cytogenetic response2.
71.8% of all ≥2nd-line patients achieved or maintained MMR by 4 years (n=149)
The results shown below are based on a data cut-off of September 2018 (≥1 year after last enrolled patient and ~85% with ≥2-year follow-up)2
1% of the patient safety population discontinued due to diarrhoea
TEAE rates* before and after dose reduction3
MMR before and after dose reduction3
A Phase 3 study in patients with newly diagnosed CP Ph+ CML.4
A long-term analysis in CP, AP, or BP Ph+ CML patients with resistance or intolerance to prior therapy.5-7
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PP-UNP-IRL-0176. January 2023