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AboutTherapeutic IndicationsRheumatoid arthritisJuvenile idiopathic arthritisPsoriatic arthritisAxial spondyloarthritisPlaque psoriasis & Paediatric plaque psoriasisMechanism of actionMechanism of actionDosingDosingRheumatoid arthritis, psoriatic arthritis & axial spondyloarthritisJuvenile idiopathic arthritisPlaque psoriasisPaediatric plaque psoriasisAdministration & storageAdministrationMYCLIC®StorageEfficacy & SafetyEfficacy & SafetyRheumatoid arthritisAxial spondyloarthritisPsoriatic arthritisPlaque psoriasisJuvenile idiopathic arthritisSupport & ResourcesMaterials
DosingJuvenile idiopathic arthritis

    Patients treated with Enbrel should be given the Patient Card.

    The recommended dose of Enbrel for JIA patients is weight-based:1

  • 0.4mg/kg (up to a maximum of 25mg per dose) given as a subcutaneous injection twice weekly at an interval of 3-4 days between doses,or
  • 0.8 mg/kg (up to a maximum of 50 mg per dose) given once weekly
  • No formal clinical trials have been conducted in children aged 2 to 3 years. However, limited safety data from a patient registry suggest that the safety profile in children from 2 to 3 years of age is similar to that seen in adults and children aged 4 years and older, when dosed every week with 0.8 mg/kg subcutaneously
  • There is generally no applicable use of Enbrel in children aged below 2 years in the indication juvenile idiopathic arthritis.

Discontinuation of treatment should be considered in JIA patients who show no response after 4 months. The 10 mg vial strength may be more appropriate for children below the weight of 25 kg1

Dosing options adapted from Enbrel Summary of Product Characteristics1JIA: Juvenile idiopathic arthritis.Explore more Efficacy & Safety

Learn more about the efficacy and safety of Enbrel in JIA

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Dosing Support & Resources

Pfizer has resources available to support you and your Enbrel patients


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Adverse events should be reported. Report an adverse event to your national reporting system (HPRA Pharmacovigilance)

Adverse events should also be reported to Pfizer Medical Information on 1800 633 363

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