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IBRANCE is indicated for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer:
In pre- or peri-menopausal women, the endocrine therapy should be combined with a luteinising hormone-releasing hormone (LHRH) agonist.1
Please see Full Prescribing lnformation and Patient lnformation
PALOMA was the first clinical trial programme to explore how a CDK4/6 inhibitor could benefit women with HR+/HER2- mBC10
With RCT data,1-6 IBRANCE RWE7-9 can help improve understanding of outcomes in patients with HR+/HER2- mBC and help you to better support your patients
Please note the materials are intended for healthcare professionals to effectively support patient care.
A broad range of women with HR+/HER2- mBC may benefit from IBRANCE combination therapy.1-9 IBRANCE is the first CDK4/6 inhibitor supported by data from clinical trials1-4 and real-world evidence.5-7
Legal Category: S1A
Further information is available upon request
Adverse events should be reported. Report an adverse event to your national reporting system (HPRA Pharmacovigilance)
Adverse events should also be reported to Pfizer Medical Information on 1800 633 363
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PP-UNP-IRL-0176. January 2023