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AboutInfliximabWhat is infliximabMechanism of actionBiosimilarsApprovalOverviewPosition statementsECCOEULARESPGHANDosing & SwitchingDosingIV dosingAdministration & storageIV administrationStorageSafety informationImportant safety informationSwitchingConsiderations for switchingSafety informationImportant safety informationSafety informationImportant safety informationClinical EvidenceRandomised controlled trial evidenceSummary: randomised controlled trial evidenceSupport & ResourcesMaterials
Considerations for switching to INFLECTRA® (CT-P13*/infliximab)

A number of experts support prescriber-initiated switching, but emphasise the importance of joint decision-making between healthcare providers and patients1-4

  • Patient involvement can be vital, and no switching should occur without patient consent or knowledge1
Review local resourcePatient booklet on biosimilars

Pfizer has produced a patient friendly booklet 'What do I need to know about Biosimilar Medicines?' which may be helpful during the switching conversation

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* CT-P13 is marketed under different brand names including INFLECTRA® and REMSIMA™.

Please refer to the INFLECTRA® Summary of Product Characteristics for full prescribing information

References:Danese S, et al. J Crohns Colitis 2017;11:26-34. Kay J, et al. Ann Rheum Dis 2018;77:165-74. Gabi online. Spanish gastroenterologists update biosimilar position statement. 30 March 2018. Available at: http://www.gabionline.net/Biosimilars/General/Spanish-gastroenterologists-update-biosimilar-position-statement. Accessed May 2023. Crohn’s & Colitis Foundation. Biosimilars Position Statement. Available at: https://www.crohnscolitisfoundation.org/sites/default/files/2019-06/biosimilars-statement-needs.pdf. Accessed May 2023.Edwards CJ, et al. Expert Opin Biol Ther 2019;19:1001-14.Armuzzi A, et al. J Crohns Colitis 2019;13:259-66.Razanskaite V, et al. J Crohns Colitis 2017;11:690-6.
Clinical evidence

INFLECTRA® infusion therapy (CT-P13) has been evaluated across 5 randomised controlled trials

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PP-IFA-IRL-0166 October 2023

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