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Experience with INLYTA® extends beyond 10 years.1
INLYTA® delivered superior progression-free survival (PFS) and objective response rate (ORR) outcomes versus sorafenib in adult patients with advanced renal cell carcinoma after first-line sunitinib or a cytokine in a phase III second line setting.1,2
Adapted from INLYTA® Summary of Product Characteristics.
*Scans assessed by blinded independent radiology review.1,2
Time from randomisation to progression or death due to any cause, whichever occurs first. Cutoff date: 03 June 2011
Risk ratio is used for ORR. A risk ratio > 1 indicated a higher likelihood of responding in the axitinib arm; a risk ratio < 1 indicated a higher likelihood of responding in the sorafenib arm.
Data adapted from INLYTA® Summary of Product Characteristics.
*ORR is derived from complete and partial response as per RECIST.1,2
Data cutoff date: 31 August 2010
Real-world evidence supports clinical trial outcomes with INLYTA® in second line.1–5
Data adapted from Melichar B, et al. 2015. Matias M, et al. 2017. Facchini G, et al. 2019.
No cross trial comparisons may be made since trials were conducted using different methodologies and at different time points.
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PP-UNP-IRL-0176. January 2023