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DosingSafetyClinical TrialsClinical TrialsXALKORI Clinical TrialsROS1+ NSCLC: PROFILE 1001ALK+ NSCLC: PROFILE 1014

Real World Evidence

Real World EvidenceReal World EvidenceSequential XALKORI® and Ceritinib in ALK+ NSCLCXALKORI® and Post-Progression Treatment in ALK+ NSCLC


The information on this website is based on data from adult patients with ALK (anaplastic lymphoma kinase)-positive / ROS 1-positive advanced NSCLC (non small cell lung cancer) treated with XALKORI®(crizotinib), produced in line with the XALKORI®(crizotinib) Summary of Product Characteristics. XALKORI® (crizotinib) Prescribing Information click here. Adverse event reporting information can be found at the bottom of the page.

XALKORI® (crizotinib):

An Established Inhibitor of ALK and ROS1

XALKORI® as monotherapy is indicated for:1

  • First-line treatment of adults with anaplastic lymphoma kinase (ALK)- positive advanced non-small cell lung cancer (NSCLC)
  • Treatment of adults with previously treated ALK-positive advanced NSCLC
  • Treatment of adults with ROS1-positive advanced NSCLC
  • Treatment of paediatric patients (age ≥ 6 to < 18 years) with relapsed or refractory systemic ALK-positive anaplastic large cell lymphoma (ALCL)
  • Treatment of paediatric patients (age ≥ 6 to < 18 years) with recurrent or refractory ALK-positive unresectable inflammatory myofibroblastic tumour (IMT)
The information on this website is based on data from adult patients with NSCLC only.
Dosing

Information on dosing, dose modifications and monitoring requirements for XALKORI®

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Clinical Trials

Clinical trial information, including study design and efficacy results

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Safety

Important safety information and safety outcomes from XALKORI® clinical trials

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Resources

Designed to support you and your patients with ALK+ or ROS1+ advanced NSCLC

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ALCL: anaplastic large cell lymphoma, ALK: anaplastic lymphoma kinase, IMT: inflammatory myofibroblastic tumour, NSCLC: non-small cell lung cancer

Reference

XALKORI® Summary of Product Characteristics  
PP-XLK-IRL-0258 February 2024 Legal Category S1A Further Information is available on request

Adverse events should be reported. Report an adverse event to your national reporting system (HPRA Pharmacovigilance)
 

Adverse events should also be reported to Pfizer Medical Information on 1800 633 363

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