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DosingSafetyClinical TrialsClinical TrialsXALKORI Clinical TrialsROS1+ NSCLC: PROFILE 1001ALK+ NSCLC: PROFILE 1014

Real World Evidence

Real World EvidenceReal World EvidenceSequential XALKORI® and Ceritinib in ALK+ NSCLCXALKORI® and Post-Progression Treatment in ALK+ NSCLC


The information on this website is based on data from adult patients with ALK (anaplastic lymphoma kinase)-positive / ROS 1-positive advanced NSCLC (non small cell lung cancer) treated with XALKORI®(crizotinib), produced in line with the XALKORI®(crizotinib) Summary of Product Characteristics. XALKORI® (crizotinib) Prescribing Information click here. Adverse event reporting information can be found at the bottom of the page.

XALKORI® Real World Evidence

RWE and data from RCTs each have their own complementary strengths and weaknesses that, when combined, help regulators, clinicians and patients to better understand and utilise therapies.1-3

Please note, observational retrospective analyses are not intended for direct comparison with clinical trials due to differences in study design and settings.

Progression-Free and Overall Survival in ALK+ NSCLC Patients Treated with Sequential XALKORI® and Ceritinib

Data from a multicentre cohort, retrospective study (n=73)4

Learn MoreLoadingOverall Survival With XALKORI® and Post-Progression Treatments in Patients with Advanced ALK+ NSCLC

Data from a French cohort, retrospective study (n=318)​​​​​​​5

Learn MoreLoading

ALK: anaplastic lymphoma kinase, NSCLC: non-small cell lung cancer, RCT: randomised controlled trial, RWE: real world evidence

References

de Lusignan S, et al. J Innov Health Inform 2015;22:368–373.Khozin S, et al. J Natl Cancer Inst 2017;109:djx187.Singal AG, et al. Clin Transl Gastroenterol 2014;5:e45.Gainor JF, et al. Clin Cancer Res. 2015;21(12):2745-52.Duruisseaux M, et al. Oncotarget. 2017;8(13):21903-17
PP-XLK-IRL-0264 February 2024 Legal Category S1A Further information is available on request

Adverse events should be reported. Report an adverse event to your national reporting system (HPRA Pharmacovigilance)
 

Adverse events should also be reported to Pfizer Medical Information on 1800 633 363

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