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Zavicefta® (ceftazidime-avibactam) for proven precise destruction1,2Zavicefta® (ceftazidime-avibactam) for proven precise destruction1,2Targeted efficacy against a broad range of MDR Gram-negative pathogens2–4Targeted efficacy against a broad range of MDR Gram-negative pathogens2–4Broad Coverage Discover More Efficacy Discover More Safety Discover More Adult Dosing Discover More Prescribing information

Zavicefta® (avibactam sodium, ceftazidime pentahydrate)

Zavicefta® (avibactam sodium, ceftazidime pentahydrate) 2g/0.5g powder for concentrate for solution for infusion

ZAVICEFTA has in vitro activity against pathogens producing AmpC, ESBL, KPC and OXA-48 enzymes.2
ZAVICEFTA’s range of in vitro activity against β-lactamases does not necessarily predict clinical success.
ZAVICEFTA has no in vitro activity against pathogens producing class B metallo-β-lactamases and is not able to inhibit many class D enzymes.2
Abbreviations:ESBL, extended spectrum β-lactamase; KPC, Klebsiella pneumoniae carbapenemase; OXA, oxacillinase; MDR, multi drug resistant.References:Zhang W, et al. Antimicrob Resist Infect Control 2018:7;142.ZAVICEFTA. Summary of Product Characteristics, 2022.Mazuski JE, et al. Clin Infect Dis 2016;62:1380–9.Liscio JL, et al. Int J Antimicrob Agents 2015;46:266–71.

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