Conjugate Vaccines

Prevenar 13^® is a conjugate vaccine¹

Conjugate vaccines function differently than polysaccharide vaccines^2,3

Can adults receive both Prevenar 13^® and PPV?

In instances where both Prevenar 13^® and PPV23 are recommended, PCV should be given first, followed by PPV23 at least 2 months later. If PPV23 has been given first, wait at least 1 year before giving PCV. ⁴

References

1. Prevenar 13^® Summary of Product Characteristics. November 2020
2. Pollard AJ, Perrett KP, Beverley PC. Maintaining protection against invasive bacteria with protein-polysaccharide conjugate vaccines. Nat Rev Immunol. 2009;9(3):213-220
3. Goldblatt D. Conjugate vaccines. Clin Exp Immunol. 2000;119(1):1-3
4. NIAC Guidelines Chapter 16: Pneumococcal Infection