Conjugate Vaccines

Prevenar 13® is a conjugate vaccine1

Conjugate vaccines function differently than polysaccharide vaccines2,3

Conjugate Vaccines

Can adults receive both Prevenar 13® and PPV?

In instances where both Prevenar 13® and PPV23 are recommended, PCV should be given first, followed by PPV23 at least 2 months later. If PPV23 has been given first, wait at least 1 year before giving PCV. 4


  1. Prevenar 13® Summary of Product Characteristics. November 2020
  2. Pollard AJ, Perrett KP, Beverley PC. Maintaining protection against invasive bacteria with protein-polysaccharide conjugate vaccines. Nat Rev Immunol. 2009;9(3):213-220
  3. Goldblatt D. Conjugate vaccines. Clin Exp Immunol. 2000;119(1):1-3
  4. NIAC Guidelines Chapter 16: Pneumococcal Infection

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