ZAVICEFTA (ceftazidime and avibactam) Mechanism of Action



Introducing ZAVICEFTA: A combination of ceftazidime and avibactam1 

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ZAVICEFTA: Potent inhibitory activity against difficult-to-treat infections due to Gram-negative bacteria1,2 

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*Avibactam does not inhibit class B enzymes (metallo-β-lactamases) and is not able to inhibit many class D enzymes.1 

References:
1
. ZAVICEFTA. Summary of product characteristics, 2018.
2. Liscio JL, et al. Int J Antimicrob Agents 2015;46:266–71.
3. Ehmann DE, et al. PNAS 2012;109:11663–8.