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Hospitalisation DataAim for Reduced Hospitalisation Burden1

In a retrospective analysis of data from the INO-VATE ALL study; of the patients who received at least one dose of study drug (BESPONSA n=164 vs SC n=143), BESPONSA reduced hospitalisation burdens when compared with standard chemotherapy.1

Hospitalisation for both groups was mainly for treatment of underlying disease and toxicity associated with R/R ALL treatment including haematologic toxicity and infection.1

IRR=incidence rate ratio; SC=standard chemotherapy.Lower Percentage of Treatment Time Spent in Hospital for BESPONSA vs SC1Overall, 136 of 164 (82.9%) BESPONSA patients and 135 of 143 (94.4%) SC patients experienced at least one hospitalisation.1
BESPONSA patients spent substantially longer on treatment vs SC patients: 85 days vs 45 days per patient (in total 13,946 days vs 6,463 days), respectively.1*Treatment of underlying disease includes hospitalisations for scheduled treatment related to ALL or study participation, relapse and preparation for HSCT.ALL=acute lymphoblastic leukemia; HSCT=hematopoietic stem cell transplantation; SC=standard chemotherapy.
ALL=acute lymphoblastic leukemia; EMD=extramedullary disease; R/R=relapsed/refractory; SmPC=Summary of Product Characteristics.References:Marks DI, et al. Cancer Med. 2019;8(13):5959-5968.
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