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Mechanism of Action  Dosing Dosing Dosing Information Dose Adjustments Drug Interactions Efficacy & Trial Design Efficacy Efficacy Trial Design Safety & Tolerability Support & ResourcesSupport &
​​​​​​​Resources Materials Videos Frequently Asked Questions
PAXLOVID is taken orally, twice daily for 5 days1Treatment should begin as soon as possible following a positive COVID-19 test and ≤5 days of symptom onset.For 5 consecutive days1 Morning Dose
  • Two pink 150-mg tablets of 
    ​​​​nirmatrelvir
  • One white 100-mg tablet of ritonavir

Patients should take all 3 tablets together.

 Evening Dose
  • Two pink 150-mg tablets of 
    nirmatrelvir
  • One white 100-mg tablet of ritonavir

Patients should take all 3 tablets together.

PAXLOVID dosing instructions1
  • PAXLOVID can be taken with or without food
  • The tablets should be swallowed whole and not chewed, broken, or crushed
  • Patients must complete the full treatment course, even if they begin to feel better
  • If a dose of PAXLOVID is missed within 8 hours of the time it is usually taken, the patient should take it as soon as possible and resume the normal dosing schedule. If the patient misses a dose by more than 8 hours, the patient should not take the missed dose and instead take the next dose at the regularly scheduled time. The patient should not double the dose to make up for a missed dose
EXPLORE MOREEfficacy & trial design

Discover the efficacy data and trial design of EPIC-HR. 

 Efficacy Loading Trial design LoadingReferences:
  1. PAXLOVID Summary of Product Characteristics. https://www.medicines.ie/medicines/paxlovid-150-mg-100-mg-film-coated-tablets-35210/spc (Accessed October 2023).
Dosing Drug Interaction Finder

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▼ This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions. See section 4.8 of the SmPC for how to report adverse reactions.

Legal Category: S1A
Further information is available upon request

PP-PAX-IRL-0171. October 2023

Adverse events should be reported. Report an adverse event to your national reporting system (HPRA Pharmacovigilance)
 

Adverse events should also be reported to Pfizer Medical Information on 1800 633 363

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