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Regardless of prior TNFi use, XELJANZ was more effective than placebo at 10mg BID1
Central reading of endoscopic findings was used for eligibility and primary and key secondary efficacy endpoint analyses.1
In OCTAVE Induction 1, patients had a mean Total Mayo score of 9 at baseline (n=598). 51% had previously failed TNFi; 75% corticosteroids; 74% lmmunosuppressant therapy. Previous treatment failure was determined by the Investigator.
In OCTAVE Induction 2, patients had a mean Total Mayo score of 9 at baseline (n=541 ). 52% had previously failed TNFi; 71 % corticosteroids; 69% immunosuppressant therapy. Previous treatment failure was determined by the investigator.
BID=twice daily; TNFi=tumour necrosis factor inhibitor.
Regardless of prior TNFi use, XELJANZ was more effective than placebo in maintaining remission.
Please refer to the XELJANZ Summary of Product Characteristics for full prescribing information
Learn more about the XELJANZ safety profile
Learn about dosing in UC
Find out more about how XELJANZ works
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PP-UNP-IRL-0176. January 2023