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XELJANZ should only be used if no suitable treatment alternatives are available in patients:
-65 years of age and older;
-patients with history of atherosclerotic cardiovascular disease or other cardiovascular risk factors (such as current or past long-time smokers);
-patients with malignancy risk factors (e.g. current malignancy or history of malignancy)
Considering the increased risk of serious infections, myocardial infarction, malignancies and all cause mortality with XELJANZ in patients 65 years of age and older, XELJANZ should only be used in these patients if no suitable treatment alternatives are available (see further details in section 4.4 and section 5.1 of the XELJANZ Summary of Product Characteristics).
Please refer to the XELJANZ Summary of Product Characteristics for full prescribing information
BMI=body mass index; IL-1R=interleukin-1 receptor; IL-6R=interleukin-6 receptor; RA=rheumatoid arthritis; TNF=tumor necrosis factor.
Learn more about the XELJANZ safety profile, supported by up to 9.5 years of long-term data
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Adverse events should be reported. Report an adverse event to your national reporting system (HPRA Pharmacovigilance)
Adverse events should also be reported to Pfizer Medical Information on 1800 633 363
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PP-UNP-IRL-0176. January 2023