Data described here are reflective of the 476 patients treated with LORVIQUA in the Phase 1/2 study of previously treated patients and the Phase 3 CROWN study of previously untreated patients.1,2
The most common adverse reactions are reported below.
Adverse reaction | All grades | Grades 3 and 4 |
---|---|---|
Hypercholesterolaemiaa | 81.1% | 18.3% |
Hypertriglyceridaemiab | 67.2% | 19.3% |
Oedemac | 55.7% | 2.7% |
Peripheral neuropathyd | 43.7% | 2.7% |
Weight increased | 30.9% | 10.1% |
Cognitive effectse | 27.7% | 2.9% |
Fatiguef | 27.3% | 1.3% |
Arthralgia | 23.5% | 0.8% |
Diarrhoea | 22.9% | 1.5% |
Mood effectsg | 21.0% | 1.5% |
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PP-UNP-IRL-0784. June 2024