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EfficacyEfficacy Home PageTrial DesignClinical RemissionEarly Symptomatic ResponseEndoscopic ImprovementBio/JAKi Subgroups DataIsolated ProctitisSafetyAdverse eventsCardiac and ocular adverse eventsGetting StartedResourcesMaterialsVideosPrescribing InformationPrescribing Information 
Biologic/JAKi Subgroups Data

ELEVATE UC 52

ELEVATE UC 12

Tab Number 3

Tab Number 4

Tab Number 5

Oral advanced therapy* use supported by VELSIPITY® efficacy in biologic/JAKi subgroupsIn ELEVATE UC 52, patients on Velsipity® who had previous exposure to Biologic/JAKI achieved clinical remission.1,2†
Advanced therapies include S1P receptor modulators, biologics, and JAK inhibitors.3Clinical remission was defined as a stool frequency (SF) subscore of 0 (or of 1 with a ≥1-point decrease from baseline), a rectal bleeding (RB) subscore of 0, and an endoscopy score (ES) ≤1 (excluding friability).1
Oral advanced therapy* use supported by VELSIPITY® efficacy in biologic/JAKi subgroupsIn ELEVATE UC 12, patients on Velsipity® who had previous exposure to Biologic/JAKi achieved clinical remission.1,2†
Advanced therapies include S1P receptor modulators, biologics, and JAK inhibitors.3Clinical remission was defined as a stool frequency (SF) subscore of 0 (or of 1 with a ≥1-point decrease from baseline), a rectal bleeding (RB) subscore of 0, and an endoscopy score (ES) ≤1 (excluding friability).1
▼ This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions. See section 4.8 of the SmPC for how to report adverse reactions.References:VELSIPITY® (etrasimod) Summary of Product Characteristics. Available online at medicines.ie.Sandborn WJ, Vermeire S, Peyrin-Biroulet L, et al. Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies [published correction appears in Lancet. 2023;401(10381):1000]. Lancet. 2023;401(10383):1159-1171. Supplementary appendix available at: https://www.thelancet.com/cms/10.1016/S0140-6736(23)00061-2/attachment/cdbbc759-490f-4b2a-a3a2-93bc9918b29f/mmc1.pdf. Accessed December 18, 2023.Sandborn WJ, Vermeire S, Peyrin-Biroulet L, et al. Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies [published correction appears in Lancet. 2023;401(10381):1000]. Lancet. 2023;401(10383):1159-1171.
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PP-V1A-0024 Date of preparation February 2025
Isolated Proctitis

See how VELSIPITY® is effective in calming the chaos of isolated proctitis.

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