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EfficacyEfficacy Home PageTrial DesignClinical RemissionEarly Symptomatic ResponseEndoscopic ImprovementBio/JAKi Subgroups DataIsolated ProctitisSafetyAdverse eventsCardiac and ocular adverse eventsGetting StartedResourcesMaterialsVideosPrescribing InformationPrescribing Information 
Clinical Remission

ELEVATE UC 52

ELEVATE UC 12

Tab Number 3

Tab Number 4

Tab Number 5

VELSIPITY®helped patients calm the chaos of UC1

Significant and sustained clinical remission* vs placebo in ELEVATE UC 521

2 in 3 patients taking VELSIPITY® who achieved clinical remission at week 12 sustained it at week 521

ReferencesClinical remission was defined as a stool frequency (SF) subscore of 0 (or of 1 with a ≥1-point decrease from baseline), a rectal bleeding (RB) subscore of 0, and an endoscopy score (ES) ≤1 (excluding friability).1Corticosteroid-free remission was defined as remission at week 52 without receiving corticosteroids for ≥12 weeks prior to week 52.1Investigators were directed to taper corticosteroids in ELEVATE UC 52 after the week 12 assessment.2Early symptomatic responseSee how VELSIPITY® offered symptomatic response as early as day 2. SEE SYMPTOMATIC RESPONSE Loading▼ This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions. See section 4.8 of the SmPC for how to report adverse reactions.References:VELSIPITY® (etrasimod) Summary of Product Characteristics. Available online at medicines.ie.Sandborn WJ, Vermeire S, Peyrin-Biroulet L, et al. Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies [published correction appears in Lancet. 2023;401(10381):1000]. Lancet. 2023;401(10383):1159-1171.Legal Category S1A
Further information available on request

PP-V1A-0024 Date of preparation February 2025
VELSIPITY® helped patients calm the chaos of UC1Significant clinical remission* vs placebo in ELEVATE UC 121 ReferencesClinical remission was defined as a stool frequency (SF) subscore of 0 (or of 1 with a ≥1-point decrease from baseline), a rectal bleeding (RB) subscore of 0, and an endoscopy score (ES) ≤1 (excluding friability).1Early symptomatic responseSee how VELSIPITY® offered symptomatic response as early as day 2. SEE SYMPTOMATIC RESPONSE LoadingReferences:VELSIPITY® (etrasimod) Summary of Product Characteristics. Available online at medicines.ie. ▼ This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions. See section 4.8 of the SmPC for how to report adverse reactions

Legal Category S1A
Further information available on request

PP-V1A-0024 Date of preparation February 2025
Efficacy

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