This site is intended only for healthcare professionals resident in the Republic of Ireland

Search

Menu

Close

Sign in or registerLog out
Our medicinesTherapy areasExplore contentExplore contentMaterialsVideosPodcasts3D Body AtlasLet’s connectLet's connectContact usSign up

Adverse event reporting can be found at the bottom of the page

Home

Menu

Close

EfficacyEfficacy Home PageTrial DesignClinical RemissionEarly Symptomatic ResponseEndoscopic ImprovementBio/JAKi Subgroups DataIsolated ProctitisSafetyAdverse eventsCardiac and ocular adverse eventsGetting StartedResourcesMaterialsVideosPrescribing InformationPrescribing Information 
Endoscopic Improvement

ELEVATE UC 52

ELEVATE UC 12

Tab Number 3

Tab Number 4

Tab Number 5

A greater proportion of patients experienced endoscopic improvement with VELSIPITY® vs placebo1

VELSIPITY® reduced inflammation in the colon in ELEVATE UC 52, further demonstrating the effectiveness of treatment1

ReferencesEndoscopic improvement was defined as an endoscopy score (ES) ≤1 (excluding friability).1Mucosal healing

VELSIPITY® demonstrated mucosal healing in patients living with UC

A greater proportion of patients experienced mucosal healing with VELSIPITY® vs placebo in ELEVATE UC 521

 ReferencesMucosal healing was defined as an endoscopy score (ES) ≤1 (excluding friability) with histologic remission (Geboes Index score <2.0, indicating no neutrophils in the epithelial crypts or lamina propria, no increase in eosinophils, and no crypt destruction, erosions, ulcerations, or granulation tissue).1Efficacy in biologic/JAKi subgroupSee how effective VELSIPITY® was in patients who were previously exposed to advanced therapies. EXPLORE SUBGROUPLoading▼ This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions. See section 4.8 of the SmPC for how to report adverse reactions.Reference:VELSIPITY® (etrasimod) Summary of Product Characteristics. Available online at www.medicines.ie.
A greater proportion of patients experienced endoscopic improvement with VELSIPITY® vs placebo1

VELSIPITY® reduced inflammation in the colon in ELEVATE UC 12, further demonstrating the effectiveness of treatment1

ReferencesEndoscopic improvement was defined as an endoscopy score (ES) ≤1 (excluding friability).1Mucosal healing

VELSIPITY® demonstrated mucosal healing in patients living with UC

A greater proportion of patients experienced mucosal healing with VELSIPITY® vs placebo in ELEVATE UC 121

 ReferencesMucosal healing was defined as an endoscopy score (ES) ≤1 (excluding friability) with histologic remission (Geboes Index score <2.0, indicating no neutrophils in the epithelial crypts or lamina propria, no increase in eosinophils, and no crypt destruction, erosions, ulcerations, or granulation tissue).1Efficacy in biologic/JAKi subgroupSee how effective VELSIPITY® was in patients who were previously exposed to advanced therapies. EXPLORE SUBGROUPLoading▼ This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions. See section 4.8 of the SmPC for how to report adverse reactions.Reference:VELSIPITY® (etrasimod) Summary of Product Characteristics. Available online at www.medicines.ie.
EfficacyLegal Category S1A
Further information available on request.

PP-V1A-IRL-0024 Date of preparation February 2025

Adverse events should be reported.

If you wish to make a medical information inquiry or report an adverse event please contact Pfizer on 1800 633 363 
or email Pfizer at [email protected] or visit www.PfizerMedicalInformation.ie

Report an adverse event to your national reporting system (HPRA Pharmacovigilance)

PfizerPro AccountPfizerPro Account

Please sign in or register to gain access to information relating to Pfizer medicines and vaccines, medical conditions, patient materials and services.

Sign in or RegisterRegisterAccountLog out

This site is intended only for healthcare professionals resident in the Republic of Ireland. If you are a member of the public wishing to access information on a specific medicine, please visit https://www.medicines.ie

 

This website is brought to you by Pfizer Healthcare Ireland Unlimited Company, The Watermarque Building, Ringsend Road, Dublin 4, Dublin, Ireland, D04 K7N3.Registered in the Republic of Ireland No. 127002. Directors: M. Adamson (Managing), O. Gavan, D. Kennedy. Company Secretary: M.Byrne.

 

Copyright © 2025 Pfizer Limited. All rights reserved.

PP-UNP-IRL-0937. July 2025
You are now leaving PfizerPro
You are now leaving PfizerPro Ireland. Links to external websites are provided as a resource to the viewer. This website is neither owned nor controlled by Pfizer. Pfizer accepts no responsibility for the content or services of the linked site.


PP-UNP-IRL-0901. July 2025
For Healthcare Professionals in the Republic of Ireland *

The information on this site is reserved exclusively for healthcare professionals resident in the Republic of Ireland and contains promotional content.

I confirm that I am a healthcare professional* resident in the Republic of Ireland.

If you select 'No', you will be redirected to Pfizer.ie, where you will be able to access information on Pfizer Healthcare Ireland Unlimited Company.

*The IPHA Code definition of a healthcare professional is a person of any of the following classes: (i) Registered medical practitioners (ii) Registered dentists (iii) Registered pharmacists (iv) Registered nurses

Terms of use

PP-UNP-IRL-0901. July 2025

Yes No